What kind of Scientific Question and Neuroscience Experiments Design can the NIRS and EEG systems offer related to Human Connectome or Functional Connectivity?

04/08/2023 at 06:08:30

Scientific Question and Neuroscience 2023 Experiments Design

NIRS (Near-Infrared Spectroscopy) and EEG (Electroencephalography) are valuable neuroimaging techniques that can be used to study human connectome and functional connectivity. They offer unique advantages in investigating brain networks and understanding how different brain regions communicate and interact. Here are some scientific questions and neuroscience experiments designs that NIRS and EEG systems can address:

Examining Brain Network Connectivity:

Scientific Question: How are different brain regions functionally connected during specific cognitive tasks or resting states?

Neuroscience Experiments Design: In a resting-state experiment, participants would be asked to lie still with their eyes closed while their brain activity is recorded using NIRS and/or EEG. Functional connectivity analysis would then be conducted to investigate synchronous activity patterns between different brain regions in the absence of a specific task.

Investigating Brain Connectivity Changes in Neurological Disorders:

Scientific Question: How does brain connectivity differ in individuals with neurological disorders compared to healthy controls?

Neuroscience Experiments Design: Participants from both groups (healthy and with neurological disorders) would undergo NIRS and/or EEG recordings during specific cognitive tasks or at rest. Functional connectivity measures would be compared between the groups to identify differences associated with the neurological condition.

Assessing Developmental Changes in Brain Connectivity:

Scientific Question: How does functional connectivity change in the developing brain from infancy to adulthood?

Neuroscience Experiments Design: Longitudinal studies involving NIRS and/or EEG would be conducted on participants at different age groups, capturing brain activity during various cognitive tasks or at rest. Comparing functional connectivity patterns across different ages would reveal developmental changes in brain networks.

Brain Connectivity and Cognitive Performance:

Scientific Question: Is there a relationship between functional connectivity patterns and cognitive performance in specific tasks?

Neuroscience Experiments Design: Participants would perform cognitive tasks while their brain activity is recorded using NIRS and/or EEG. The strength of functional connectivity between relevant brain regions would be correlated with their cognitive performance to explore potential associations.

Brain Connectivity in Response to Stimulation or Interventions:

Scientific Question: How does brain connectivity change in response to external stimuli or interventions?

Neuroscience Experiments Design: Participants would undergo specific interventions, such as sensory stimulation or cognitive training, while their brain activity is recorded with NIRS and/or EEG. Changes in functional connectivity before and after the intervention would be analyzed to assess its effects on brain networks.

Overall, NIRS and EEG systems offer valuable tools to study the human connectome and functional connectivity in different experimental setups and populations. Their non-invasive nature and high temporal resolution make them particularly suitable for investigating brain network dynamics and understanding how brain regions interact to support various cognitive functions and behaviors.

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Question, Physical Principles and Experimental Designs

Ritmos Cerebrais e Conectividade | Functional Connectivity

Functional Connectivity

Human Connectome | Functional Connectivity